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doi: 10.1159/000454683

Figure 5 Contrary to the results obtained after modification in the C-terminal of Ang IV where essentially all compounds examined exhibited some activity, oxidative cyclization of the side chains of Cys 1 and Cys 3 and consequently creation of an 11-membered disulfide macrocycle in the N-terminal rendered the inactive compound 20 (Figure 6)

Health conditions exacerbated by excess weight, such as diabetes or high blood pressure

Both classes have demonstrated cardio-renal benefits, favorable safety profiles, and reduced polypharmacy

GHK-Cu is present in various human biological fluids, including plasma, saliva, and urine